Specialist Dataset

Deeply-phenotyped hospital COVID patients: Acuity, severity, therapies, outcomes

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Some individuals experience severe manifestations of Covid-19 infection, including viral pneumonia, adult respiratory distress syndrome (ARDS) and death. There is a pressing need for tools to stratify patients, to identify those at greatest risk. Acuity scores are composite scores which help identify patients who are more unwell to support and prioritise clinical care. There are no validated acuity scores for COVID-19 and it is unclear whether standard tools are accurate enough to provide this support. This secondary care COVID dataset contains granular demographic, morbidity, serial acuity and outcome data to inform risk prediction tools in COVID-19.

PIONEER geography

The West Midlands (WM) has a population of 5.9 million & includes a diverse ethnic & socio-economic mix. There is a higher than average percentage of minority ethnic groups. WM has a large number of elderly residents but is the youngest population in the UK.  Each day >100,000 people are treated in hospital, see their GP or are cared for by the NHS. The West Midlands was one of the hardest hit regions for COVID admissions in both wave 1 & 2.

EHR

University Hospitals Birmingham NHS Foundation Trust (UHB) is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & 100 ITU beds. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”.  UHB has cared for >5000 COVID admissions to date.

Scope

All COVID swab confirmed hospitalised patients to UHB from January – May 2020.  The dataset includes highly granular patient demographics & co-morbidities taken from ICD-10 & SNOMED-CT codes but also primary care records& clinic letters.  Serial, structured data pertaining to care process (timings, staff grades, specialty review, wards), presenting complaint, acuity, all physiology readings (pulse, blood pressure, respiratory rate, oxygen saturations), all blood results, microbiology, all prescribed & administered treatments (fluids, antibiotics, inotropes, vasopressors, organ support), all outcomes.  Linked images available (radiographs, CT, MRI, ultrasound).

Available supplementary data

Health data preceding and following admission event. Matched “non-COVID” controls; ambulance, 111, 999 data, synthetic data.

Available supplementary support

Analytics, model build, validation & refinement; A.I.; Data partner support for ETL (extract, transform & load) process, clinical expertise, patient and end-user access, purchaser access, regulatory requirements, data-driven trials, 'fast screen' services.

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