Delirium is a clinical syndrome of acute confusion which is particularly common in critically ill Intensive Care patients. Delirium on ICU is associated with adverse health outcomes including increased mortality, length of stay, readmission, discharge to long term care, dementia, falls and pressure sores. It can be distressing for both the person affected and their family and carers. Delirium on ICU can be triggered by medications, especially those with an anticholinergic effect.
PIONEER has curated a highly granular dataset of 9,100 spells admitted to intensive care. This includes timestamped medication prescriptions and administration with cognition scores. Also, demography, serial physiology, consult specialties, diagnostic codes (ICD-10 & SNOMED-CT), initial presentation, presenting symptoms, serial physiology, all investigations, all medications (name, dose, route), anticholinergic burden (AEC) scores, and outcomes. The current dataset includes admissions from 01-01-2021 to 31-12-2023 but can be expanded to assess other timelines of interest.
Geography: The West Midlands (WM) has a population of 6 million & includes a diverse ethnic & socio-economic mix. UHB is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & > 120 ITU bed capacity. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”.
Data set availability: Data access is available via the PIONEER Hub for projects which will benefit the public or patients. This can be by developing a new understanding of disease, by providing insights into how to improve care, or by developing new models, tools, treatments, or care processes. Data access can be provided to NHS, academic, commercial, policy and third sector organisations. Applications from SMEs are welcome. There is a single data access process, with public oversight provided by our public review committee, the Data Trust Committee. Contact [email protected] or visit www.pioneerdatahub.co.uk for more details.
Available supplementary data: Matched controls; ambulance and community data. Unstructured data (images). We can provide the dataset in OMOP and other common data models and can build synthetic data to meet bespoke requirements.
Available supplementary support: Analytics, model build, validation & refinement; A.I. support. Data partner support for ETL (extract, transform & load) processes. Bespoke and “off the shelf” Trusted Research Environment (TRE) build and run. Consultancy with clinical, patient & end-user and purchaser access/ support. Support for regulatory requirements. Cohort discovery. Data-driven trials and “fast screen” services to assess population size.
Further information including technical details, coverage, format and standards, provenance and related resources can be found on the link below: https://healthdatagateway.org/en/dataset/995
